Condition: Addiction


Cannabis use disorder and adverse cardiovascular outcomes: A population-based retrospective cohort analysis of adults from Alberta, Canada

Abstract Aim To measure the association between cannabis use disorder (CUD) and adverse cardiovascular disease (CVD) outcomes. Design and Setting We conducted a matched, population-based retrospective cohort study involving five…

Use of Cannabis as a Harm Reduction Strategy Among People Who Use Drugs: A Cohort Study

Please use this link to access this publication: https://www.liebertpub.com/doi/full/10.1089/can.2021.0229 Abstract Introduction: While substance use contributes to a substantial burden of disease, access to evidence-based harm reduction interventions remains limited or inaccessible. Preliminary…

Cannabis use to manage opioid cravings among people who use unregulated opioids during a drug toxicity crisis

Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0955395923001603 Abstract Background Accumulating evidence has indicated that cannabis substitution is often used as a harm reduction strategy among people who use unregulated…

Cannabidiol regulation of emotion and emotional memory processing: relevance for treating anxiety‐related and substance abuse disorders

Abstract Learning to associate cues or contexts with potential threats or rewards is adaptive and enhances survival. Both aversive and appetitive memories are therefore powerful drivers of behaviour, but the…

Cannabidiol for the Reduction of Cue-Induced Craving and Anxiety in Drug-Abstinent Individuals With Heroin Use Disorder: A Double-Blind Randomized Placebo-Controlled Trial

Abstract Objective: Despite the staggering consequences of the opioid epidemic, limited nonopioid medication options have been developed to treat this medical and public health crisis. This study investigated the potential of…

Factors associated with alcohol consumption among medical cannabis patients with chronic pain

Abstract Introduction: Chronic pain is the most common reason for medical cannabis certification. Data regarding alcohol use and risky drinking among medical cannabis patients with pain is largely unknown. Therefore, we…

Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010

Link to Read Article: https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/1898878 Abstract Importance  Opioid analgesic overdose mortality continues to rise in the United States, driven by increases in prescribing for chronic pain. Because chronic pain is a major…

Association between medical cannabis laws and opioid overdose mortality has reversed over time

Abstract Medical cannabis has been touted as a solution to the US opioid overdose crisis since Bachhuber et al. [M. A. Bachhuber, B. Saloner, C. O. Cunningham, C. L. Barry, JAMA…

Recreational cannabis legalization has had limited effects on a wide range of adult psychiatric and psychosocial outcomes

Abstract Background. The causal impacts of recreational cannabis legalization are not well understood due to the number of potential confounds. We sought to quantify possible causal effects of recreational cannabis…

Recreational Cannabis Legalization and Opioid-Related Deaths in Colorado, 2000-2015

Abstract   Objectives: To examine the association between Colorado’s legalization of recreational cannabis use and opioid-related deaths.   Methods: We used an interrupted time-series design (2000-2015) to compare changes in level and…