Condition: Addiction

Interactions between delta9-tetrahydrocannabinol and heroin: self-administration in rhesus monkeys

The cannabinoid receptor agonist delta9 -tetrahydrocannabinol (THC) enhances the antinociceptive effects of mu opioid receptor agonists, raising the possibility of using a combination of THC and opioids for treating pain….

Involvement of the endocannabinoid system in drug addiction

Recent studies have shown that the endocannabinoid system is involved in the common neurobiological mechanism underlying drug addiction. This system participates in the primary rewarding effects of cannabinoids, nicotine, alcohol…

Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010

Opioid analgesic overdose mortality continues to rise in the United States, driven by increases in prescribing for chronic pain. Because chronic pain is a major indication for medical cannabis, laws that…

Cannabidiol as an Intervention for Addictive Behaviors: A Systematic Review of the Evidence

Drug addiction is a chronically relapsing disorder characterized by the compulsive desire to use drugs and a loss of control over consumption. Cannabidiol (CBD), the second most abundant component of…