Abstract Rationale Delta-9-tetrahydrocannabinol (THC), an active component of cannabis, can cause anxiety in some users during intoxication. Cannabidiol (CBD), another constituent of cannabis, has anxiolytic properties suggesting that cannabis products…
Condition: Anxiety
Cannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice
Abstract The anxiolytic and antidepressant properties of cannabidiol (CBD) have been evaluated in several studies. However, the molecular mechanisms involved in these actions remain unclear. A total of 130 male…
New Insights and Potential Therapeutic Targeting of CB2 Cannabinoid Receptors in CNS Disorders
Abstract The endocannabinoid system (ECS) is ubiquitous in most human tissues, and involved in the regulation of mental health. Consequently, its dysregulation is associated with neuropsychiatric and neurodegenerative disorders. Together,…
Cannabinoid treatments for anxiety: A systematic review and consideration of the impact of sleep disturbance
Please use this link to access this publication. Abstract Cannabidiol’s (CBD) safety profile and broad action has made it a popular treatment option for anxiety and co-occurring sleep disturbance. However,…
Wound healing efficacy of Cannabis sativa L. essential oil in a mouse incisional wound model: A possible link with stress and anxiety
Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0254629923006804 Abstract Cannabis Sativa L. (Cannabaceae) exerts biological effects through its bioactive compounds. Cannabis Sativa L. essential oil (CSEO) is known to have antibacterial properties that can accelerate wound…
Subjective, behavioral and neurobiological effects of cannabis and cannabinoids in social anxiety
Please use this link to access this publication: https://www.degruyter.com/document/doi/10.1515/revneuro-2023-0078/html Abstract Social anxiety disorder (SAD) is a debilitating disorder, characterized by fear and anxiety in social situations. Evidence suggests that the levels…
Comparing the effects of medical cannabis for chronic pain patients with and without co-morbid anxiety: A cohort study
ABSTRACT Introduction There is growing evidence on the efficacy of cannabis-based medicinal products (CBMPs) for chronic pain (CP). Due to the interaction between CP and anxiety, and the potential impact…
The “Entourage Effect”: Terpenes Coupled with Cannabinoids for the Treatment of Mood Disorders and Anxiety Disorders
Abstract Mood disorders are the most prevalent mental conditions encountered in psychiatric practice. Numerous patients suffering from mood disorders present with treatment-resistant forms of depression, co-morbid anxiety, other psychiatric disorders…
Action of cannabidiol on the anxiety and other effects produced by δ9-THC in normal subjects
Please use this link to access this publication: https://link.springer.com/article/10.1007/BF00432554 Abstract The object of the experiment was to verify whether cannabidiol (CBD) reduces the anxiety provoked by Δ 9-TCH in normal volunteers, and whether…
Involvement of serotonin-mediated neurotransmission in the dorsal periaqueductal gray matter on cannabidiol chronic effects in panic-like responses in rats
Please use this link to access this publication: https://link.springer.com/article/10.1007/s00213-012-2878-7 Abstract Rationale: Cannabidiol (CBD) is a non-psychotomimetic constituent of Cannabis sativa plant that promotes antianxiety and anti-panic effects in animal models after acute…