Opinion statement The potential medicinal properties of Cannabis continue to garner attention, especially in the brain tumor domain. This attention is centered on quality of life and symptom management; however, it is…
Condition: Brain Function
A randomised, placebo-controlled, double blind, crossover trial on the effect of a 20:1 cannabidiol: Δ9-tetrahydrocannabinol medical cannabis product on neurocognition, attention, and mood
Abstract As cannabinoid-based medications gain popularity in the treatment of refractory medical conditions, it is crucial to examine the neurocognitive effects of commonly prescribed products to ensure associated safety profiles….
Chronic effects of cannabis use on the human reward system: An fMRI study
Please use this link to access this publication. Abstract Cannabis is one of the most used drugs of abuse. It affects the brain reward system in animals, and has proven…
Individual and Additive Effects of the CNR1 and FAAH Genes on Brain Response to Marijuana Cues
Abstract As previous work has highlighted the significance of the cannabinoid receptor 1 (CNR1) and fatty acid amide hydrolase (FAAH) genes with respect to cannabis dependence (CD), this study sought to characterize the neural mechanisms that…
Structural MRI Findings in Long-Term Cannabis Users: What Do We Know?
Please use this link to access this publication. Abstract In animal studies, tetrahydrocannabinol (THC) has been found to affect brain morphology, particularly within areas rich in cannabinoid receptors (e.g., hippocampus,…
THC and endocannabinoids differentially regulate neuronal activity in the prefrontal cortex and hippocampus in the subchronic PCP model of schizophrenia
Please use this link to access this publication. Abstract Cannabis use has been associated with an increased risk to develop schizophrenia as well as symptom exacerbation in patients. In contrast,…
The effect of five day dosing with THCV on THC-induced cognitive, psychological and physiological effects in healthy male human volunteers: A placebo-controlled, double-blind, crossover pilot trial
Please use this link to access this publication. Abstract Rationale: Cannabis is mostly grown under illegal and unregulated circumstances, which seems to favour a product increasingly high in its main…
The effects of Δ9-tetrahydrocannabinol on the dopamine system
Please use this link to access this publication. Abstract The effects of Δ9-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, are a pressing concern for global mental health. Patterns of…
Effects of tetrahydrocannabinol on glucose uptake in the rat brain
Please use this link to access this publication. Abstract Δ9-Tetrahydrocannabinol (THC) is the psychoactive component of the plant Cannabis sativa and acts as a partial agonist at cannabinoid type 1 and type 2 receptors in the brain….
Marijuana effects on changes in brain structure and cognitive function among HIV+ and HIV− adults
Please use this link to access this publication. Abstract Background The current study examined the independent and interactive effects of HIV and marijuana (MJ) use on brain structure and cognitive…