Condition: Cannabis Use Disorder


A large-scale genome-wide association study meta-analysis of cannabis use disorder

Summary Background Variation in liability to cannabis use disorder has a strong genetic component (estimated twin and family heritability about 50–70%) and is associated with negative outcomes, including increased risk…

Nabiximols as an agonist replacement therapy during cannabis withdrawal: a randomized clinical trial

Abstract Importance: There are no medications approved for treating cannabis dependence or withdrawal. The cannabis extract nabiximols (Sativex), developed as a multiple sclerosis treatment, offers a potential agonist medication for cannabis…

Treatment of Cannabis Use Disorders: A Review of the Literature

Please use this link to access this publication. Abstract Cannabis is the most widely used illicit drug in the United States. Despite the fact that there are large numbers of…

Genetic basis of cannabis use: a systematic review

Abstract Background With the increase in cannabis use rates, cannabis use disorder is being reported as one of the most common drug use disorders globally. Cannabis use has several known…

A positive association between anxiety disorders and cannabis use or cannabis use disorders in the general population- a meta-analysis of 31 studies

Abstract Background The aim of the current study was to investigate the association between anxiety and cannabis use/cannabis use disorders in the general population. Methods A total of N = 267 studies were…

Association of cannabis potency with mental ill health and addiction: a systematic review

Please use this link to access this publication. Summary Cannabis potency, defined as the concentration of Δ9-tetrahydrocannabinol (THC), has increased internationally, which could increase the risk of adverse health outcomes…

Exploring the Link Between Attention-Deficit Hyperactivity Disorder and Cannabis Use Disorders: A Review

Abstract Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder in children and adults. In the substance use disorders (SUDs) population, ADHD prevalence reaches 23.1%, leading to more severe substance abuse…

The prevalence of cannabis use disorders in people who use medicinal cannabis: A systematic review and meta-analysis

Abstract Background: The prevalence of cannabis use disorders (CUDs) in people who use cannabis recreationally has been estimated at 22%, yet there is a dearth of literature exploring CUDs among people…