Abstract Mood disorders are the most prevalent mental conditions encountered in psychiatric practice. Numerous patients suffering from mood disorders present with treatment-resistant forms of depression, co-morbid anxiety, other psychiatric disorders…
Condition: Depression
Antidepressant-like effects of Δ⁹-tetrahydrocannabinol and rimonabant in the olfactory bulbectomised rat model of depression
Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S009130571200144X?via%3Dihub Abstract The endocannabinoid signalling system is widely accepted to play a role in controlling the affective state. Plant cannabinoids are well known…
Antidepressant-like effect of delta9-tetrahydrocannabinol and other cannabinoids isolated from Cannabis sativa L
Abstract The antidepressant action of cannabis as well as the interaction between antidepressants and the endocannabinoid system has been reported. This study was conducted to assess the antidepressant-like activity of…
Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels
Abstract Cannabidiol (CBD) is a compound of Cannabis sativa with relevant therapeutic potential in several neuropsychiatric disorders including depression. CBD treatment has shown significant antidepressant-like effects in different rodent preclinical…
Effects of Chronic Cannabidiol Treatment in the Rat Chronic Unpredictable Mild Stress Model of Depression
Abstract Several neuropharmacological actions of cannabidiol (CBD) due to the modulation of the endocannabinoid system as well as direct serotonergic and gamma-aminobutyric acidergic actions have recently been identified. The current…
Chronic administration of synthetic cannabidiol induces antidepressant effects involving modulation of serotonin and noradrenaline levels in the hippocampus
Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0304394020308648?via%3Dihub Abstract Cannabidiol (CBD) is a non-psychotomimetic compound derived from Cannabis sativa. Preclinical and clinical studies have shown therapeutic potential of CBD in…
Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0028390815302136?via%3Dihub Abstract Cannabidiol (CBD), the main non-psychotomimetic component of marihuana, exhibits anxiolytic-like properties in many behavioural tests, although its potential for treating major…
Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors
Abstract Background and purpose: Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that induces anxiolytic- and antipsychotic-like effects in animal models. Effects of CBD may be mediated by the activation…
Association of Cannabis With Long-Term Clinical Symptoms in Anxiety and Mood Disorders: A Systematic Review of Prospective Studies
Please use this link to access this publication: https://www.psychiatrist.com/jcp/cannabis-and-anxiety-and-mood-disorders/ Abstract Objective: To systematically review studies examining the longitudinal associations between cannabis use and symptomatic outcomes among individuals with an anxiety or mood…
The association between cannabis use and depression: a systematic review and meta-analysis of longitudinal studies
Please use this link to access this publication: https://www.cambridge.org/core/journals/psychological-medicine/article/abs/association-between-cannabis-use-and-depression-a-systematic-review-and-metaanalysis-of-longitudinal-studies/B144B7AE5A3D973289DBDD99ADE21E58 Abstract BackgroundLongitudinal studies reporting the association between cannabis use and developing depression provide mixed results. The objective of this study was to…