Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0304394020308648?via%3Dihub Abstract Cannabidiol (CBD) is a non-psychotomimetic compound derived from Cannabis sativa. Preclinical and clinical studies have shown therapeutic potential of CBD in…
Condition: Depression
Cannabidiol induces rapid-acting antidepressant-like effects and enhances cortical 5-HT/glutamate neurotransmission: role of 5-HT1A receptors
Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0028390815302136?via%3Dihub Abstract Cannabidiol (CBD), the main non-psychotomimetic component of marihuana, exhibits anxiolytic-like properties in many behavioural tests, although its potential for treating major…
Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors
Abstract Background and purpose: Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that induces anxiolytic- and antipsychotic-like effects in animal models. Effects of CBD may be mediated by the activation…
Association of Cannabis With Long-Term Clinical Symptoms in Anxiety and Mood Disorders: A Systematic Review of Prospective Studies
Please use this link to access this publication: https://www.psychiatrist.com/jcp/cannabis-and-anxiety-and-mood-disorders/ Abstract Objective: To systematically review studies examining the longitudinal associations between cannabis use and symptomatic outcomes among individuals with an anxiety or mood…
The association between cannabis use and depression: a systematic review and meta-analysis of longitudinal studies
Please use this link to access this publication: https://www.cambridge.org/core/journals/psychological-medicine/article/abs/association-between-cannabis-use-and-depression-a-systematic-review-and-metaanalysis-of-longitudinal-studies/B144B7AE5A3D973289DBDD99ADE21E58 Abstract BackgroundLongitudinal studies reporting the association between cannabis use and developing depression provide mixed results. The objective of this study was to…
Self-medication of mood and anxiety disorders with marijuana: Higher in states with medical marijuana laws
Abstract Background Self-medication with drugs or alcohol is commonly reported among adults with mood or anxiety disorders, and increases the risk of developing substance use disorders. Medical marijuana laws (MML)…
Psychoneuroendocrinological links between chronic stress and depression
Abstract Objective: The goal of this report is to develop a comprehensive model, which integrates psychosocial and neurobiological aspects, for better understanding the link between chronic stress and mood disorders….
A possible role for the endocannabinoid system in the neurobiology of depression
Abstract The present review synthetically describes the currently advanced hypotheses for a neurobiological basis of depression, ranging from the classical monoaminergic to the more recent neurotrophic hypothesis. Moreover, the…
Endocannabinoid system: Role in depression, reward and pain control (Review)
Abstract Depression and pain co-exist in almost 80% of patients and are associated with impaired health-related quality of life, often contributing to high mortality. However, the majority of patients…
Antidepressant-like effect induced by Cannabidiol is dependent on brain serotonin levels
Abstract Cannabidiol (CBD) is a compound of Cannabis sativa with relevant therapeutic potential in several neuropsychiatric disorders including depression. CBD treatment has shown significant antidepressant-like effects in different rodent preclinical models. However,…