Please use this link to access this publication. Abstract Cannabidiol (CBD) is the main non-psychotropic component of the glandular hairs of Cannabis sativa. It displays a plethora of actions including anticonvulsive,…
Condition: Nervous System
Cannabinoids to Improve Health-Related Quality of Life in Patients with Neurological or Oncological Disease: A Meta-Analysis
Abstract Background: Cannabinoids have been suggested to alleviate frequently experienced symptoms of reduced mental well-being such as anxiety and depression. Mental well-being is an important subdomain of health-related quality of life…
Δ9-Tetrahydrocannabinol promotes oligodendrocyte development and CNS myelination in vivo
Abstract Δ9-Tetrahydrocannabinol (THC), the main bioactive compound found in the plant Cannabis sativa, exerts its effects by activating cannabinoid receptors present in many neural cells. Cannabinoid receptors are also physiologically…
Δ9-Tetrahydrocannabinol promotes functional remyelination in the mouse brain
Abstract Background and purpose Research on demyelinating disorders aims to find novel molecules that are able to induce oligodendrocyte precursor cell differentiation to promote central nervous system remyelination and functional…
Impairment of Synaptic Plasticity by Cannabis, Δ9-THC, and Synthetic Cannabinoids
Abstract The ability of neurons to dynamically and flexibly encode synaptic inputs via short- and long-term plasticity is critical to an organism’s ability to learn and adapt to the environment….
Short and long-term neuroprotective effects of cannabidiol after neonatal peripheral nerve axotomy
Please use this link to access this publication. Abstract Neonatal rat sciatic nerve crush mimics obstetric axonotmesis, leading to extensive loss of motor and sensory neurons. The present study aimed…
Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
Abstract Cannabidiol (CBD) exhibits anti-inflammatory and neuroprotective properties and is suggested to be effective in the pre-clinical and clinical treatment of illnesses of the central nervous system (CNS). Two major…
In Vitro Studies on Therapeutic Effects of Cannabidiol in Neural Cells: Neurons, Glia, and Neural Stem Cells
Abstract (‒)-Cannabidiol (CBD) is one of the major phytocannabinoids extracted from the Cannabis genus. Its non-psychoactiveness and therapeutic potential, partly along with some anecdotal—if not scientific or clinical—evidence on the…
Neuropathic itch treated with oral cannabinoids: A case series
Introduction Neuropathic pruritus is defined as an itch arising from diseases of the central or peripheral nervous system, including nerve damage, compression, or irritation. It can be generalized or localized…
Cannabinoid receptor activation acutely increases synaptic vesicle numbers by activating synapsins in human synapses
Please use this link to access this publication. Abstract Cannabis and cannabinoid drugs are central agents that are used widely recreationally and are employed broadly for treating psychiatric conditions. Cannabinoids…