Abstract The discovery of endocannabinoid’s role within the central nervous system and its potential therapeutic benefits have brought forth rising interest in the use of cannabis for medical purposes. The…
Condition: Parkinson’s Disease
Cannabis (Medical Marijuana) Treatment for Motor and Non–Motor Symptoms of Parkinson Disease An Open-Label Observational Study
Please use this link to access this publication. Abstract Objective The use of cannabis as a therapeutic agent for various medical conditions has been well documented. However, clinical trials in…
Long-term safety of medical cannabis in Parkinson’s disease: A retrospective case-control study
Please use this link to access this publication. Abstract Background: Whole-plant medical cannabis (MC) products are widely used for controlling symptoms associated with Parkinson’s disease (PD). Despite its widespread use, few…
Medical Cannabis in the Treatment of Parkinson’s Disease
Please use this link to access this publication. Abstract Objectives: Medical cannabis (MC) has recently garnered interest as a potential treatment for neurologic diseases, including Parkinson’s disease (PD). A retrospective chart…
Medicinal cannabis in neurodegenerative disorders: an open label, dose finding, safety and efficacy study
Please use this link to access this publication. Abstract Aim: Currently, there exist no curative treatments for neurodegenerative disorders. Recently, there has been a resurgence of interest in the use of…
Cannabidiol-Δ9-tetrahydrocannabinol interactions on acute pain and locomotor activity
Please use this link to access this publication. Abstract Background Previous studies suggest that cannabidiol (CBD) may potentiate or antagonize Δ9-tetrahydrocannabinol’s (THC) effects. The current study examined sex differences in CBD modulation…
Cannabidiol increases the nociceptive threshold in a preclinical model of Parkinson’s disease
Please use this link to access this publication. Abstract Medications that improve pain threshold can be useful in the pharmacotherapy of Parkinson’s disease (PD). Pain is a prevalent PD’s non-motor symptom with a higher…
Cannabidiol exerts protective effects in an in vitro model of Parkinson’s disease activating AKT/mTOR pathway
Please use this link to access this publication. Abstract Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the degeneration of the nigrostriatal dopaminergic pathway with loss of substantia nigra pars compacta neurons…
Cannabis Dopaminergic Effects Induce Hallucinations in a Patient with Parkinson’s Disease
Abstract Cannabis products that contain the tetrahydrocannabinol (THC) cannabinoid are emerging as promising therapeutic agents for the treatment of medical conditions such as chronic pain. THC elicits psychoactive effects through…