Abstract One of the unique features of prenatal alcohol exposure in humans is impaired cognitive and behavioral function resulting from damage to the central nervous system (CNS), which leads to…
Condition: Pregnancy
Cannabidiol changes P-gp and BCRP expression in trophoblast cell lines
Objectives. Marijuana is the most commonly used illicit drug during pregnancy. Due to high lipophilicity, cannabinoids can easily penetrate physiological barriers like the human placenta and jeopardize the developing fetus….
Five-year Follow-up of Rural Jamaican Children whose Mothers used Marijuana during Pregnancy
This research provides data on the development of 59 Jamaican children, from birth to age 5 years, whose mothers used marijuana during pregnancy. Approximately one-half of the sample used marijuana…
Identifying Prenatal Cannabis Exposure and Effects of Concurrent Tobacco Exposure on Neonatal Growth
BACKGROUND: Cannabis is the most frequently used illicit drug among pregnant women, but data describing the effects of prenatal cannabis exposure and concurrent nicotine and cannabis exposures on neonatal growth…
Lasting impacts of prenatal cannabis exposure and the role of endogenous cannabinoids in the developing brain
Cannabis is the most commonly used illicit substance among pregnant women. Human epidemiological and animal studies have found that prenatal cannabis exposure influences brain development and can have long-lasting impacts…
Ligand-receptor signaling with endocannabinoids in preimplantation embryo development and implantation
Although adverse effects of cannabinoids on pregnancy have been indicated for many years, the mechanisms by which they exert their actions were not clearly understood. Only recently, molecular and biochemical…
Maternal Marijuana Use During Lactation and Infant Development at One Year
Prenatal marijuana exposure is associated with adverse perinatal effects. Very little is known about the effect of postnatal marijuana exposure on infant development. Postnatal exposure can result from maternal use…
Multiple Roles for the Endocannabinoid System During the Earliest Stages of Life: Pre- and Postnatal Development
The endocannabinoid system, including its receptors (CB1 and CB2), endogenous ligands (‘endocannabinoids’), synthesising and degrading enzymes, as well as transporter molecules, has been detected from the earliest stages of embryonic…
Prenatal Marijuana Exposure and Neonatal Outcomes in Jamaica: An Ethnographic Stud
OBJECTIVE: To identify neurobehavioral effects of prenatal marijuana exposure on neonates in rural Jamaica. DESIGN: Ethnographic field studies and standardized neuro-behavior assessments during the neonatal period. SETTING: Rural Jamaica in…
A Longitudinal Study of Prenatal Marijuana Use Effects on Sleep and Arousal at Age 3 Years
Objective: To test the hypothesis that sleep disruptions would be evident in 3-year-old children with a history of prenatal marijuana exposure. Design: A prospective study using stratified random sampling beginning…