OBJECTIVE: To evaluate the transfer of delta-9- tetrahydrocannabinol and its metabolites into human breast milk after maternal inhalation of 0.1 g cannabis containing 23.18% delta-9-tetrahydrocannabinol. METHODS: In this pilot pharmacokinetic…
Condition: Pregnancy
Cannabinoid exposure during pregnancy and its impact on immune function
Abstract Cannabinoids are the most commonly abused illicit drugs worldwide. While cannabis can be beneficial for certain heath conditions, abuse of potent synthetic cannabinoids has been on the rise. Exposure…
Birth outcomes associated with cannabis use before and during pregnancy
INTRODUCTION: This study aimed to examine the association between cannabis use before and during pregnancy and birth outcomes. RESULTS: Overall, 26.3% of women reported previous use of cannabis and 2.6%…
The use of cannabis for Hyperemesis Gravidarum (HG)
Abstract Background: Hyperemesis Gravidarum (HG) responds only partially to standard antiemetic medications. Cannabis has been known to possess antiemetic effects and there are several medicinal cannabinoids used as anti -emetics…
Marijuana Use and Maternal Experiences of Severe Nausea During Pregnancy in Hawai‘i
Abstract Recreational use of marijuana is relatively common in the United States, and medicinal use is gaining popular and legal support. Marijuana has been proposed as a potential treatment for…
Endocannabinoid system and pregnancy
Abstract The endocannabinoid system (eCS), is a complex system, comprising the main endogenous ligands anandamide and 2-arachidonoyl glycerol, the cannabinoid receptors CB1 and CB2 and the biosynthetic and degrading enzymes….
Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4
Abstract Background: Maternal cannabis use in pregnancy is linked with long-term adverse behavioral outcomes in offspring. Epigenetic processes established in utero that affect dopaminergic (reward) signaling may mediate risks. Associations between…
Marijuana Use During Pregnancy and Lactation
ABSTRACT: Cannabis sativa (marijuana) is the illicit drug most commonly used during pregnancy. The self reported prevalence of marijuana use during pregnancy ranges from 2% to 5% in most studies….
Marijuana Use During Pregnancy and Breastfeeding: Implications for Neonatal and Childhood Outcomes
Marijuana is one of the most widely used substances during pregnancy in the United States. Emerging data on the ability of cannabinoids to cross the placenta and affect the development…