Rationale: Given the inconclusive science on the long-term effects of marijuana exposure on lung function, the increasing tetrahydrocannabinol composition of marijuana over time, and the increasing legal accessibility of the…
Condition: Pulmonary Function
Preclinical Assessment of Novel Therapeutics on the Cough Reflex: Cannabinoid Agonists as Potential Antitussives
Cough, a reflex defense mechanism, is a common symptom of many airway inflammatory diseases. At present there are no satisfactory treatments for cough that have an acceptable side effect profile….
Marijuana, Tetrahydrocannabinol, and Pulmonary Antibacterial Defenses
Although marijuana is now consumed extensively, little is known of its biologic effects on the lung. To study this problem, the intrapulmonary inactivation of an aerosolized challenge of Staphylococcus aureus…
Marijuana and chronic obstructive lung disease: a population-based study
Background: Our aim was to determine the combined and independent effects of tobacco and marijuana smoking on respiratory symptoms and chronic obstructive pulmonary disease (COPD) in the general population. Method:…
Evaluation of Serum Cytokines Levels and the Role of Cannabidiol Treatment in Animal Model of Asthma
Asthma represents a public health problem and traditionally is classified as an atopic disease, where the allergen can induce clinical airway inflammation, bronchial hyperresponsiveness, and reversible obstruction of airways. Studies…
Effects of Marijuana Smoking on the Lung
Regular smoking of marijuana by itself causes visible and microscopic injury to the large airways that is consistently associated with an increased likelihood of symptoms of chronic bronchitis that subside…
Does smoking marijuana increase the risk of chronic obstructive pulmonary disease?
Given the increased risk of chronic obstructive pulmonary disease (COPD) among smokers of tobacco, there is concern that a similar risk may exist among smokers of marijuana. A limited body…
Cannabinoid effects on ventilation and breathlessness: A pilot study of efficacy and safety
Based on the neurophysiology of dyspnoea and the distribution of cannabinoid receptors within the central nervous system, we hypothesize that the unpleasantness of breathlessness will be ameliorated in humans by…
Association Between Marijuana Exposure and Pulmonary Function Over 20 Years
Context: Marijuana smoke contains many of the same constituents as tobacco smoke, but whether it has similar adverse effects on pulmonary function is unclear. Objective: To analyze associations between marijuana…