Please use this link to access this publication. Abstract With the legalization of marijuana (Cannabis sativa) and increasing use during pregnancy, it is important to understand its impact on exposed…
Condition: Reproductive System
Cannabinoid signalling and effects of cannabis on the male reproductive system
Please use this link to access this publication. Abstract Marijuana is the most widely consumed recreational drug worldwide, which raises concerns for its potential effects on fertility. Many aspects of…
Cannabis alters DNA methylation at maternally imprinted and autism candidate genes in spermatogenic cells
ABSTRACT Cannabis use in the United States is increasing, with highest consumption among men attheir peak reproductive years. We previously demonstrated widespread changes in spermDNA methylation with cannabis exposure in…
Effects of recreational cannabis on testicular function in primary infertile men
Abstract Background Male factor contributes to up to 50% of cases of couples experiencing infertility. Cannabis is one of the most commonly used recreational drugs, and its effects on the…
Sperm DNA methylation alterations from cannabis extract exposure are evident in offspring
Abstract Background Cannabis legalization is expanding and men are the predominant users. We have limited knowledge about how cannabis impacts sperm and whether the effects are heritable. Results Whole genome…
Cannabis and metformin on diabetic male Wistar rat sperm and reproductive organ parameters
Please use this link to access this publication Abstract Purpose Cannabis use has reportedly increased in type 2 diabetic users as a possible co-treatment for associated pain and inflammation. Both…
PMON252 Δ-9-tetrahydrocannabinol does not affect motility, morphology or viability, but alters the transcriptome of cryopreserved sperm
Abstract Cannabis is one of the most widely consumed recreational drugs among reproductive aged adults around the globe. It is known that Δ-9-tetrahydrocannabinol (THC), the psychoactive component of cannabis, can…
Medical Cannabis for Gynecologic Pain Conditions
Please use this link to access publication OBJECTIVE: The endocannabinoid system is involved in pain perception and inflammation. Cannabis contains delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), which are cannabinoids that bind…
Inhibition of human androgen receptor by delta 9-tetrahydro-cannabinol and cannabidiol related to reproductive dysfunction: A computational study
Please use this link to access publication Abstract There have been conflicting reports on the impact of Cannabis sativa impact on reproductive function. Hence this study was aimed to ascertain the impact…
EVIDENCE FOR DIFFERENTIAL EFFECTS OF Δ9-THC (Δ9-TETRAHYDROCANNABINOL) ON PRE- VERSUS POST-IMPLANTATION EMBRYONIC STEM CELLS
Abstract Objective Recreational marijuana use is becoming increasingly widespread. With potential implications for fertility and embryonic development, we set out to evaluate the impact of THC exposure on the pre-…