Objective To determine the dose-dependent effect of delta-9-tetrahydrocannabinol (THC) exposure on male testes and reproductive health in a nonhuman primate model. Design Research animal study. Setting Research institute. Animal(s) Adult male rhesus macaques 8–10…
Condition: Reproductive System
Delta-9-tetrahydrocannabinol increases vascular endothelial growth factor (VEGF) secretion through a cyclooxygenase-dependent mechanism in rat granulosa cells
Please use this link to access this publication Abstract While the effects of delta-9-tetrahydrocannabinol (THC), the psychoactive component of cannabis, have been studied extensively in the central nervous system, there…
Prenatal Exposure to Delta-9-tetrahydrocannabinol (THC) Alters the Expression of miR-122-5p and Its Target Igf1r in the Adult Rat Ovary
Abstract As cannabis use during pregnancy increases, it is important to understand its effects on the developing fetus. Particularly, the long-term effects of its psychoactive component, delta-9-tetrahydrocannabinol (THC), on the…
Impact of cannabinoids on pregnancy, reproductive health, and offspring outcomes
Please use this link to access this publication. Abstract Cannabis is the most commonly used federally illegal drug in the United States and the world, especially among people of reproductive age. In…
Cannabis and Cannabinoids in Reproduction and Fertility: Where We Stand
Please use this link to access this publication. Abstract Although cannabis use is increasing in general population, their prevalence among young adults is remarkably high. In recent years, their medical…
Association Between Use of Marijuana and Male Reproductive Hormones and Semen Quality
Abstract A total of 1,215 young Danish men aged 18–28 years were recruited between 2008 and 2012 when they attended a compulsory medical examination to determine their fitness for…
The association between cannabis use and testicular function in men: A systematic review and meta-analysis
Abstract Objective To evaluate the association between cannabis use and testicular function (as assessed through semen quality and serum hormone levels) in different populations. Evidence Review Systematic review…
The role of the endocannabinoid system in female reproductive tissues
There has been increasing interest in the role of endocannabinoids as critical modulators of the female reproductive processes. Endocannabinoids are natural ligands of cannabinoid, vanilloid, and peroxisome proliferator-activated receptors. Together…
Endocannabinoids and Gonadal Hormones: Bidirectional Interactions in Physiology and Behavior
Endocannabinoids act as a major neuromodulatory system in a variety of physiological and behavioral functions. Three major lines of evidence suggest that the endocannabinoid system interacts with gonadal hormones. First,…