Please use this link to access this publication. Abstract Issues. To conduct a comprehensive search of the peer-reviewed literature to assess risk of cannabis-related mortality. Approach. Systematic peer-reviewed literature searches were conducted in…
Condition: Safety
Developmental Effects of Cannabidiol and Δ9-Tetrahydrocannabinol in Zebrafish
Abstract Cannabidiol (CBD) has gained much attention in the past several years for its therapeutic potential in the treatment of drug-resistant epilepsy, such as Dravet syndrome. Although CBD has shown…
The effect of alcohol, THC and their combination on perceived effects, willingness to drive and performance of driving and non-driving tasks
Please use this link to access this publication. Abstract Background Driving under the influence of drugs (DUID) is one of the main causes of car accidents. Alcohol and marijuana are…
Long-Term Data of Efficacy, Safety, and Tolerability in a Real-Life Setting of THC/CBD Oromucosal Spray-Treated Multiple Sclerosis Patients
Please use this link to access this publication. Abstract Delta-9-tetrahydrocannabinol (THC)/cannabidiol (CBD) oromucosal spray was approved as add-on therapy for spasticity in patients with multiple sclerosis (MS). We show our…
Efficacy and Safety of Cannabidiol in Epilepsy: A Systematic Review and Meta-Analysis
Please use this link to access this publication. Abstract Background Approximately one-third of patients with epilepsy presents seizures despite adequate treatment. Hence, there is the need to search for new…
Single-Dose Pharmacokinetics and Preliminary Safety Assessment with Use of CBD-Rich Hemp Nutraceutical in Healthy Dogs and Cats
Simple Summary The use of cannabidiol (CBD)-rich hemp-based nutraceuticals is increasing in dogs and cats for disorders related to anxiety, seizures, cancer and pain. To date, there is little information…
Driving under the influence of cannabis among medical cannabis patients with chronic pain
Please use this link to access this publication. Abstract Background Driving under the influence of cannabis (DUIC) is a public health concern among those using medical cannabis. Understanding behaviors contributing to…
Safety and Efficacy of Medical Cannabis in Fibromyalgia
Abstract Background: Chronic pain may be treated by medical cannabis. Yet, there is scarce evidence to support the role of medical cannabis in the treatment of fibromyalgia. The aim of…
Multigenerational consequences of early-life cannabinoid exposure in zebrafish
Please use this link to access this publication. Abstract While Δ9-tetrahydrocannabinol (THC) has been widely studied in the realm of developmental and reproductive toxicology, few studies have investigated potential toxicities from…
Oral medicinal cannabinoids to relieve symptom burden in the palliative care of patients with advanced cancer: a double-blind, placebo controlled, randomised clinical trial of efficacy and safety of cannabidiol (CBD)
Abstract Background Despite improvements in medical care, patients with advanced cancer still experience substantial symptom distress. There is increasing interest in the use of medicinal cannabinoids, but there is little…