Please use this link to access this publication. Abstract Objective To evaluate the safety, efficacy, and tolerability of highly purified cannabidiol (CBD) for the treatment of seizures in children and…
Condition: Safety
Impact of Smoking Cannabidiol (CBD)-Rich Marijuana on Driving Ability
ABSTRACT To investigate effects of smoking cannabidiol (CBD)-rich marijuana on driving ability and determine free CBD and Δ9-tetrahydrocannabinol (THC) concentrations in capillary blood samples, a randomised, double-blind, placebo-controlled, two-way crossover…
General risks of harm with cannabinoids, cannabis, and cannabis-based medicine possibly relevant to patients receiving these for pain management: an overview of systematic reviews
Abstract The growing demand for improved pain treatments together with expanding legalization of, and access to, cannabinoids, cannabis, and cannabis-based medicines has intensified the focus on risk–benefit considerations in pain…
Safety and tolerability of natural and synthetic cannabinoids in adults aged over 50 years: A systematic review and meta-analysis
Abstract Background Cannabinoid-based medicines (CBMs) are being used widely in the elderly. However, their safety and tolerability in older adults remains unclear. We aimed to conduct a systematic review and…
Efficacy and safety of medical cannabinoids in children: a systematic review and meta-analysis
Abstract Despite the increased use of medical cannabinoids, the efficacy and safety of the treatment among children remain uncertain. The objective was to study the efficacy and safety of medical…
Metabolic Consequences of Gestational Cannabinoid Exposure
Abstract Up to 20% of pregnant women ages 18–24 consume cannabis during pregnancy. Moreover, clinical studies indicate that cannabis consumption during pregnancy leads to fetal growth restriction (FGR), which is…
Prenatal Cannabinoid Exposure: Emerging Evidence of Physiological and Neuropsychiatric Abnormalities
Abstract Clinical reports of cannabis use prevalence during pregnancy vary widely from 3% to upwards of 35% in North America; this disparity likely owing to underestimates from self-reporting in many…
Association of a Positive Drug Screening for Cannabis With Mortality and Hospital Visits Among Veterans Affairs Enrollees Prescribed Opioids
Abstract Importance: Cannabis has been proposed as a therapeutic with potential opioid-sparing properties in chronic pain, and its use could theoretically be associated with decreased amounts of opioids used and…
The current understanding of the benefits, safety, and regulation of cannabidiol in consumer products
Please use this link to access this publication. Abstract The popularity of cannabidiol (CBD) in consumer products is soaring as consumers are using CBD for general health and well-being as…
Efficacy and safety of therapeutic use of cannabis derivatives and their synthetic analogs: Overview of systematic reviews
Please use this link to access this publication. Abstract The debate on the use of cannabinoids for therapeutic purposes is constantly on the rise. This overview aimed to map the…