Cannabidiol (CBD), a major phytocannabinoid constituent of cannabis, is attracting growing attention in medicine for its anxiolytic, antipsychotic, antiemetic and anti-inflammatory properties. However, up to this point, a comprehensive literature…
Condition: Schizophrenia
Cannabidiol enhances anandamide signaling and alleviates psychotic symptoms of schizophrenia
Cannabidiol is a component of marijuana that does not activate cannabinoid receptors, but moderately inhibits the degradation of the endocannabinoid anandamide. We previously reported that an elevation of anandamide levels…
Activity of cannabis in relation to its delta’-trans-tetrahydro-cannabinol content
Conditions have been worked out for a reliable estimation of the cataleptic activity of delta’-trans-tetrahydrocannabinol (THC) after oral administration to mice, using the ring test over a period of 6…
Abnormalities in neuroendocrine stress response in psychosis: the role of endocannabinoids
The aim of this article is to summarize current evidence regarding alterations in the neuroendocrine stress response system and endocannabinoid system and their relationship in psychotic disorders such as schizophrenia….