Cannabidiol, a nonpsychoactive constituent of the Cannabis sativa plant, has been reported to act as an agonist of the vanilloid 1 channel in the transient receptor potential family (TRPV1) and…
Condition: Schizophrenia
Cannabidiol in Humans—The Quest for Therapeutic Targets
Cannabidiol (CBD), a major phytocannabinoid constituent of cannabis, is attracting growing attention in medicine for its anxiolytic, antipsychotic, antiemetic and anti-inflammatory properties. However, up to this point, a comprehensive literature…
Activity of cannabis in relation to its delta’-trans-tetrahydro-cannabinol content
Conditions have been worked out for a reliable estimation of the cataleptic activity of delta’-trans-tetrahydrocannabinol (THC) after oral administration to mice, using the ring test over a period of 6…
Abnormalities in neuroendocrine stress response in psychosis: the role of endocannabinoids
The aim of this article is to summarize current evidence regarding alterations in the neuroendocrine stress response system and endocannabinoid system and their relationship in psychotic disorders such as schizophrenia….