Condition: Stress


Effects of regular cannabis and nicotine use on acute stress responses: chronic nicotine, but not cannabis use, is associated with blunted adrenocortical and cardiovascular responses to stress

Please use this link to access this publication. Abstract Rationale Cannabis is one of the most prevalent substances used by tobacco smokers and, in light of the growing list of…

Differential sensitivity to the acute psychotomimetic effects of delta-9-tetrahydrocannabinol associated with its differential acute effects on glial function and cortisol

Please sure this link to access publication Abstract BackgroundCannabis use has been associated with psychosis through exposure to delta-9-tetrahydrocannabinol (Δ9-THC), its key psychoactive ingredient. Although preclinical and human evidence suggests…

Frequent Low-Dose Δ9-Tetrahydrocannabinol in Adolescence Disrupts Microglia Homeostasis and Disables Responses to Microbial Infection and Social Stress in Young Adulthood

Please use this link to access publication Abstract Background During adolescence, microglia are actively involved in neocortical maturation while concomitantly undergoing profound phenotypic changes. Because the teenage years are also a time…

Cannabinoid use is enhanced by stress and changes conditioned stress responses

Abstract Individuals diagnosed with post-traumatic stress disorder (PTSD) are often comorbid for substance use disorders. Cannabis is widely used by PSTD patients, and the literature is mixed on whether cannabis…

Effects of Two Cannabidiol Oil Products on Self-Reported Stress Relief: A Quasi-Experimental Study

Abstract Introduction: Estimated rates of past-month cannabidiol (CBD) use in the general public are 13–26% and emerging research examines CBD as a potential adjunct treatment for several medical conditions, including stress-related…

Wound healing efficacy of Cannabis sativa L. essential oil in a mouse incisional wound model: A possible link with stress and anxiety

Please use this link to access this publication: https://www.sciencedirect.com/science/article/abs/pii/S0254629923006804 Abstract Cannabis Sativa L. (Cannabaceae) exerts biological effects through its bioactive compounds. Cannabis Sativa L. essential oil (CSEO) is known to have antibacterial properties that can accelerate wound…

Enhancing Endocannabinoid Control of Stress with Cannabidiol

Abstract   The stress response is a well-defined physiological function activated frequently by life events. However, sometimes the stress response can be inappropriate, excessive, or prolonged; in which case, it…

5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats

Abstract   Background and purpose: Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa which induces anxiolytic- and antipsychotic-like effects in rodents. These effects could be mediated by facilitation of the endocannabinoid system…