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Research Library

CHRI curates and manages a searchable library of published scientific articles related to the health effects of cannabis.

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This library aims to empower you with knowledge but it does not replace the personalized advice and guidance a healthcare professional can provide. Before implementing any changes to your health regimen based on the contents of this library, we strongly advise you to consult with a qualified healthcare professional. Your doctor’s expertise is essential for interpreting how these insights may apply to your unique health circumstances.

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Found 2431 Results Page 22 of 244

The Heart and Cannabis (THC) Cohort: Differences in Baseline Health and Behaviors by Cannabis Use


Abstract BACKGROUND: Evidence on the cardiovascular health effects of cannabis use is limited. We designed a prospec tive cohort study of older Veterans (66 to 68 years) with coronary artery…


The Grass Might Be Greener: Medical Marijuana Patients Exhibit Altered Brain Activity and Improved Executive Function after 3 Months of Treatment


Abstract The vast majority of states have enacted full or partial medical marijuana (MMJ) programs, causing the number of patients seeking certification for MMJ use to increase dramatically in recent…


The Genetic Structure of Marijuana and Hemp


Abstract   Despite its cultivation as a source of food, fibre and medicine, and its global status as the most used illicit drug, the genus Cannabis has an inconclusive taxonomic…


The Expression Level of CB1 and CB2 Receptors Determines Their Efficacy at Inducing Apoptosis in Astrocytomas


Background: Cannabinoids represent unique compounds for treating tumors, including astrocytomas. Whether CB1 and CB2 receptors mediate this therapeutic effect is unclear. Principal Findings: We generated astrocytoma subclones that express set…


The Exploration of Cannabis and Cannabinoid Therapies for Migraine


Please use this link to access this publication. Abstract Purpose of review: There is increasing interest in the use of cannabis and cannabinoid therapies (CCT) by the general population and among…


The endogenous cannabinoid, anandamide, induces COX-2- dependent cell death in apoptosis-resistant colon cancer cells


Despite recent advances in understanding colorectal tumour biology, there is still a need to improve the 5-year survival rate of patients with colorectal cancer as approximately 40% of patients presenting…


The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2


Background and aims: Cyclooxygenase 2 (COX-2) is upregulated in most colorectal cancers and is responsible for metabolism of the endogenous cannabinoid, anandamide, into prostaglandinethanolamides (PG-EAs). The aims of this study…


The Endogenous Cannabinoid System Stimulates Glucose Uptake in Human Fat Cells via Phosphatidylinositol 3-Kinase and Calcium Dependent Mechanisms


Background: The endogenous cannabinoid system participates in the regulation of energy balance, and its dysregulation may be implicated in the pathogenesis of obesity. Adipose tissue endocannabinoids may produce metabolic and…


The Endogenous Cannabinoid System Regulates Seizure Frequency and Duration in a Model of Temporal Lobe Epilepsy


Several lines of evidence suggest that cannabinoid compounds are anticonvulsant. However, the anticonvulsant potential of cannabinoids and, moreover, the role of the endogenous cannabinoid system in regulating seizure activity has…


The Endogenous Cannabinoid System and Its Role in Nociceptive Behavior


Abstract The analgesic properties of exogenous cannabinoids have been recognized for many years and suggest a regulatory role for the endogenous cannabinoid (“endocannabinoid”) system in mammalian nociceptive pathways. The endocannabinoid…