Potential Effects of Cannabidiol as a Wake-Promoting Agent

Current Neuropharmacology
2014
Eric Murillo-Rodríguez, Andrea Sarro-Ramírez, Daniel Sánchez, Stephanie Mijangos-Moreno, Alma Tejeda-Padrón, Alwin Poot-Aké, Khalil Guzmán, Elda Pacheco-Pantoja, & Oscar Arias-Carrión

Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on Δ9 -tetrahydrocannabinol (Δ9 -THC) as it is the psychoactive constituent of Cannabis sativa (C. sativa). However, in previous years, the focus of interest in the second plant constituent with non-psychotropic properties, cannabidiol (CBD) has been enhanced. Recently, several groups have investigated the pharmacological properties of CBD with significant findings; furthermore, this compound has raised promising pharmacological properties as a wake-inducing drug. In the current review, we will provide experimental evidence regarding the potential role of CBD as a wake-inducing drug.

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