Keyword: ∆9-tetrahydrocannabinol (THC)


The Effect of Oil-Based Cannabis Extracts on Metabolic Parameters and Microbiota Composition of Mice Fed a Standard and a High-Fat Diet

Abstract The prevalence of obesity and obesity-related pathologies is lower in frequent cannabis users compared to non-users. It is well established that the endocannabinoid system has an important role in…

Cannabinoid levels description in a cohort of patients with chronic and neuropathic pain treated with Cannabis decoction: A possible role of TDM

Abstract The phytocomplex of Cannabis is made up of approximately 500 substances: terpeno-phenols metabolites, including Δ-9-tetrahydrocannabinol and cannabidiol, exhibit pharmacological activity. Medical Cannabis has several pharmacological potential applications, in particular in the management of chronic and neuropathic…

Clinical Practice Guidelines for Cannabis and Cannabinoid-Based Medicines in the Management of Chronic Pain and Co-Occurring Conditions

Abstract Background: One in five individuals live with chronic pain globally, which often co-occurs with sleep problems, anxiety, depression, and substance use disorders. Although these conditions are commonly managed with cannabinoid-based…

P947 medical cannabis increases appetite but not body weight in patients with inflammatory bowel diseases

Abstract Background Medical cannabis (MC) is prescribed to improve appetite and nutritional status in patients with inflammatory bowel diseases (IBD) despite no supporting evidence. We aimed to describe the effect…

Cannabis use may attenuate neurocognitive performance deficits resulting from methamphetamine use disorder

Abstract Objective:Methamphetamine and cannabis are two widely used, and frequently co-used, substances with possibly opposing effects on the central nervous system. Evidence of neurocognitive deficits related to use is robust…

Cannabis and cancer: unveiling the potential of a green ally in breast, colorectal, and prostate cancer

Abstract Cancer comes in second place on the list of causes of death worldwide. In 2018, the 5-year prevalence of breast cancer (BC), prostate cancer (PC), and colorectal cancer (CRC)…

A national study of clinical discussions about cannabis use among Veteran patients prescribed opioids

Abstract Background The Veterans Health Administration tracks urine drug tests (UDTs) among patients on long-term opioid therapy (LTOT) and recommends discussing the health effects of cannabis use. Objective To determine…

Limited psychological and social effects of lifetime cannabis use frequency: Evidence from a 30-year community study of 4,078 twins

Please use this link to access this publication. Abstract Background: Cannabis use is associated with outcomes like income, legal problems, and psychopathology. This finding rests largely on correlational research designs,…

Daily associations with cannabis use and sleep quality in anxious cannabis users

Please use this link to access this publication. ABSTRACT Introduction Cannabis is increasingly used to self-treat anxiety and related sleep problems, without clear evidence of either supporting or refuting its…

Daily diary study of associations between alcohol, cannabis, co-use and sleep quality in individuals with intentions to use cannabis to cope with anxiety

Abstract Introduction Sleep problems and anxiety conditions are common comorbidities and may be influenced by cannabis and alcohol use. This study examined daily within-person variation in subjective sleep quality among…