Please use this link to access this publication. Abstract Treatment-resistant epilepsy (TRE) affects 30% of epilepsy patients and is associated with severe morbidity and increased mortality. Cannabis-based therapies have been…
Keyword: ∆9-tetrahydrocannabinol (THC)
Are cannabinoids an effective and safe treatment option in the management of pain? A qualitative systematic review
Abstract Objective: To establish whether cannabis is an effective and safe treatment option in the management of pain. Design: Systematic review of randomised controlled trials. Data sources: Electronic databases Medline, Embase, Oxford Pain…
Nabiximols as an agonist replacement therapy during cannabis withdrawal: a randomized clinical trial
Abstract Importance: There are no medications approved for treating cannabis dependence or withdrawal. The cannabis extract nabiximols (Sativex), developed as a multiple sclerosis treatment, offers a potential agonist medication for cannabis…
A Randomized, Placebo-Controlled, Crossover Trial of Cannabis Cigarettes in Neuropathic Pain
Abstract The Food and Drug Administration (FDA), Substance Abuse and Mental Health Services Administration (SAMHSA), and the National Institute for Drug Abuse (NIDA) report that no sound scientific studies support…
Evidence for cannabis and cannabinoids for epilepsy: a systematic review of controlled and observational evidence
Abstract Review evidence for cannabinoids as adjunctive treatments for treatment-resistant epilepsy. Systematic search of Medline, Embase and PsycINFO was conducted in October 2017. Outcomes were: 50%+ seizure reduction, complete seizure freedom;…
Anti-Cancer Potential of Cannabinoids, Terpenes, and Flavonoids Present in Cannabis
Abstract In recent years, and even more since its legalization in several jurisdictions, cannabis and the endocannabinoid system have received an increasing amount of interest related to their potential exploitation…
Medicinal Δ9-tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests
Please use this link to access this publication. Abstract Aims The acute and chronic effects of dronabinol [medicinal Δ9-tetrahydrocannabinol (THC)] on actual driving performance and the Standard Field Sobriety Test…
Sex-Dependent Effects of Cannabis and Cannabinoids: A Translational Perspective
Abstract Recent policy changes have led to significant increases in the use of cannabis for both medical and recreational purposes. Although men are more likely to endorse past month cannabis…
Systematic review of systematic reviews for medical cannabinoids
Abstract Objective To determine the effects of medical cannabinoids on pain, spasticity, and nausea and vomiting, and to identify adverse events. Data sources MEDLINE, the Cochrane Database, and the references of included…
Association of Cannabis Use With Cardiovascular Outcomes Among US Adults
Abstract Background We examined the association between cannabis use and cardiovascular outcomes among the general population, among never‐tobacco smokers, and among younger individuals. Methods and Results This is a population‐based,…