Keyword: anti-angiogenic

The use of cannabinoids as anticancer agents

Highlights •The endocannabinoid system may play a dual role on the regulation of tumor generation and progression. •Administration of THC and other cannabinoids exert anticancer actions in animal models of…

A Cannabinoid Quinone Inhibits Angiogenesis by Targeting Vascular Endothelial Cells

Recent findings on the inhibition of angiogenesis and vascular endothelial cell proliferation by anthracycline antibiotics, which contain a quinone moiety, make this type of compound a very promising lead in…

Antiangiogenic Activity of the Endocannabinoid Anandamide: Correlation to its Tumor-Suppressor Efficacy

Endocannabinoids are now emerging as suppressors of key cell-signaling pathways involved in cancer cell growth, invasion, and metastasis. We have previously observed that the metabolically stable anandamide analog, 2-methyl-2′-F-anandamide (Met-F-AEA)…

Systematic review of the literature on clinical and experimental trials on the antitumor effects of cannabinoids in gliomas

To evaluate, through a systematic review of the literature, the antitumoral effects of cannabinoids on gliomas. Research included the following electronic databases: PUBMED, EMBASE, LILACS and The Cochrane Collaboration Controlled…