Abstract Essential oils (EOs) are volatile and concentrated liquids extracted from different parts of plants. Bioactive compounds found in EOs, especially terpenes and terpenoids possess a wide range of biological…
Keyword: anti-cancer
The use of cannabinoids as anticancer agents
Highlights •The endocannabinoid system may play a dual role on the regulation of tumor generation and progression. •Administration of THC and other cannabinoids exert anticancer actions in animal models of…
Cannabinoid receptor ligands as potential anticancer agents – high hopes for new therapies?
Objectives: The endocannabinoid system is an endogenous lipid signalling network comprising arachidonic-acid-derived ligands, cannabinoid (CB) receptors, transporters and endocannabinoid degrading enzymes. The CB1 receptor is predominantly expressed in neurons but…
The endocannabinoid system and cancer: therapeutic implication
The endocannabinoid system is implicated in a variety of physiological and pathological conditions (inflammation, immunomodulation, analgesia, cancer and others). The main active ingredient of cannabis, D9 -tetrahydrocannabinol (D9 -THC), produces…