OBJECTIVES: To review and describe studies of the non-psychotomimetic constituent of Cannabis sativa, cannabidiol (CBD), as an anxiolytic drug and discuss its possible mechanisms of action. METHOD: The articles selected for the…
Keyword: Anxiety disorders
Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABAA receptors
BACKGROUND AND PURPOSE: The aim of this study was to explore the effects of CB2 receptor agonist and antagonist in the regulation of anxiety-like behaviours. EXPERIMENTAL APPROACHES: Effects of acute…
Is cannabis treatment for anxiety, mood, and related disorders ready for prime time?
Anxiety and related disorders are the most common mental conditions affecting the North American population. Despite their established efficacy, first-line antidepressant treatments are associated with significant side effects, leading many…