Abstract Rationale: The endocannabinoid system is under active investigation as a pharmacological target for obesity management due to its role in appetite regulation and metabolism. Exogenous cannabinoids such as tetrahydrocannabinol…
Keyword: appetite
Cannabinoids and appetite: Food craving and food pleasure
Abstract The ability of Cannabis sativa to promote eating has been documented for many centuries, with the drug reported by its users to promote strong cravings for, and an intensification of the…
A cannabigerol-rich Cannabis sativa extract, devoid of ∆9- tetrahydrocannabinol, elicits hyperphagia in rats
Abstract Nonpsychoactive phytocannabinoids (pCBs) from Cannabis sativa may represent novel therapeutic options for cachexia because of their pleiotropic pharmacological activities, including appetite stimulation. We have recently shown that purified…
Cannabinoids and Cystic Fibrosis: A Novel Approach to Etiology and Therapy
Cannabis stimulates appetite and food intake. This property has been exploited to benefit AIDS and cancer patients suffering from wasting disease, by administering the whole plant or its major active…
Dronabinol and marijuana in HIV+ marijuana smokers: acute effects on caloric intake and mood
Rationale: No studies to date have directly compared the tolerability and efficacy of smoked marijuana and oral dronabinol in HIV+ marijuana smokers. Objectives: The aim of this study was to…
Endocannabinoids, feeding and suckling – from our perspective
In this overview we have summarized some aspects of our published work related to the effects of the endocannabinoid system on appetite and suckling. As noted also by several other…
Multiple Roles for the Endocannabinoid System During the Earliest Stages of Life: Pre- and Postnatal Development
The endocannabinoid system, including its receptors (CB1 and CB2), endogenous ligands (‘endocannabinoids’), synthesising and degrading enzymes, as well as transporter molecules, has been detected from the earliest stages of embryonic…
Dronabinol and marijuana in HIV+ marijuana smokers: acute effects on caloric intake and mood
Rationale: No studies to date have directly compared the tolerability and efficacy of smoked marijuana and oral dronabinol in HIV+ marijuana smokers. Objectives: The aim of this study was to…