The type 2 cannabinoid receptor (CB2R) was recently shown to mediate neuroprotection in ischemic injury. However, the role of CB2Rs in the central nervous system, especially neuronal and glial CB2Rs…
Keyword: CB2 receptor agonist/s
Activation of Cannabinoid CB2 Receptor – Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury
Activation of CB2 receptors as a potential therapeutic target for migraine: evaluation in an animal model
Background: Experimental animal models of migraine have suggested the existence of interactions between the endocannabinoid system and pain mediation in migraine. Extensive evidence has demonstrated a role for the cannabinoid-1…
Therapeutic Action of Cannabinoids in a Murine Model of Multiple Sclerosis
Theiler’s virus infection of the CNS induces an immune-mediated demyelinating disease in susceptible mouse strains and serves as a relevant infection model for human multiple sclerosis (MS). Cannabinoids may act…