Cannabinoids, the active components of Cannabis sativa (marijuana) and their endogenous counterparts, exert their effects by binding to specific G-protein-coupled receptors that modulate adenylyl cyclase and ion channels. Recent research…
Keyword: Ceramide
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R( รพ )-Methanandamide and JWH-015: Involvement of CB2
BACKGROUND: We have previously shown that cannabinoids induce growth inhibition and apoptosis in prostate cancer PC-3 cells, which express high levels of cannabinoid receptor types 1 and 2 (CB1 and…