ABSTRACT Context: Chronic pain is highly prevalent in most of the industrialized nations around the world. Despite the documented adverse effects, opioids are widely used for pain management. Cannabinoids,…
Keyword: chronic pain
Medical Cannabis Use Is Associated With Decreased Opiate Medication Use in a Retrospective Cross-Sectional Survey of Patients With Chronic Pain
Abstract Opioids are commonly used to treat patients with chronic pain (CP), though there is little evidence that they are effective for long term CP treatment. Previous studies reported…
The Effect of Medicinal Cannabis on Pain and Quality-of-Life Outcomes in Chronic Pain
Abstract Objectives: The objective of this prospective, open-label study was to determine the long-term effect of medicinal cannabis treatment on pain and functional outcomes in participants with treatment-resistant chronic pain….
Associations between medical cannabis and prescription opioid use in chronic pain patients
Abstract Background Current levels and dangers of opioid use in the U.S. warrant the investigation of harm-reducing treatment alternatives. PurposeA preliminary, historical, cohort study was used to examine the…
Cannabinoids for treatment of chronic non-cancer pain
Effective therapeutic options for patients living with chronic pain are limited. The pain relieving effect of cannabinoids remains unclear. A systematic review of randomized controlled trials (RCTs) examining cannabinoids in…
Association of Herbal Cannabis Use With Negative Psychosocial Parameters in Patients With Fibromyalgia
Objective. Patients with chronic pain, including fibromyalgia (FM), may seek treatments outside of mainstream medicine. Medicinal cannabinoids are popularly advocated for pain relief but with limited evidence for efficacy in…
Medical Marijuana: Clearing Away the Smoke
Recent advances in understanding of the mode of action of tetrahydrocannabinol and related cannabinoid ingredients of marijuana, plus the accumulating anecdotal reports on potential medical benefits have spurred increasing research…
Prescribing cannabis for harm reduction
Abstract Neuropathic pain affects between 5% and 10% of the US population and can be refractory to treatment. Opioids may be recommended as a second-line pharmacotherapy but have risks including…
The Endocannabinoid System, Cannabinoids, and Pain
Abstract The endocannabinoid system is involved in a host of homeostatic and physiologic functions, including modulation of pain and inflammation. The specific roles of currently identified endocannabinoids that act as…