Keyword: Dronabinol


Medicinal Δ9-tetrahydrocannabinol (dronabinol) impairs on-the-road driving performance of occasional and heavy cannabis users but is not detected in Standard Field Sobriety Tests

Please use this link to access this publication. Abstract Aims The acute and chronic effects of dronabinol [medicinal Δ9-tetrahydrocannabinol (THC)] on actual driving performance and the Standard Field Sobriety Test…

Pilot trial of dronabinol adjunctive treatment of agitation in Alzheimer’s disease (THC-AD)

Abstract Background Although agitation in Alzheimer’s Disease (Agit-AD) is a common and troubling neuropsychiatric syndrome, behavioral interventions lack consistent efficacy and there are no FDA-approved medications. Neurobiological mechanisms that contribute…

Dronabinol Prescribing and Exposure Among Children and Young Adults Diagnosed with Cancer

Abstract Purpose: The therapeutic utility of Cannabis in cancer is a topic of intense interest. Dronabinol is synthetic Δ9-tetrahydrocannabinol (THC), the primary psychoactive component of Cannabis sativa, and is approved for treating refractory chemotherapy-induced…

Study rationale and baseline data for pilot trial of dronabinol adjunctive treatment of agitation in Alzheimer’s dementia (THC-AD)

Please use this link to access this publication. Abstract Agitation is a common complication of Alzheimer’s dementia (Agit-AD) associated with substantial morbidity, high healthcare service utilization, and adverse emotional and…

Cannabis-based medicine in treatment of patients with Gilles de la Tourette syndrome

Abstract Introduction: Gilles de la Tourette syndrome (GTS) is a childhood onset disorder characterised by the presence of motor and vocal tics. The guidelines of both the American Academy of…

Efficacy of dronabinol as an adjuvant treatment for chronic pain patients on opioid therapy

Abstract We assessed the efficacy of dronabinol (Marinol capsules; Solvay Pharmaceuticals, Brussels, Belgium), a synthetic Delta(9)-THC (tetrahydrocannabinol), in 30 patients taking opioids for chronic pain to determine its potential analgesic…

Abuse potential assessment of cannabidiol (CBD) in recreational polydrug users

Abstract Rationale: Treatment with a highly purified oral solution of cannabidiol (CBD), derived from the plant Cannabis sativa L., demonstrated some evidence of central nervous system (CNS)-related adverse events in patients…

Use of cannabinoids for the treatment of patients with post-traumatic stress disorder

Abstract   Objectives: Post-traumatic Stress Disorder (PTSD) is a diagnosis of extreme anxiety caused by a traumatic event. Less than 10% of individuals who have experienced severe trauma will develop this…

Association of Cannabinoid Administration With Experimental Pain in Healthy Adults A Systematic Review and Meta-analysis

Abstract Importance: Cannabinoid drugs are widely used as analgesics, but experimental pain studies have produced mixed findings. The analgesic properties of cannabinoids remain unclear. Objective: To conduct a systematic review and meta-analysis…

Use of dronabinol (delta-9-THC) in autism: A prospective single-case-study with an early infantile autistic child

Objective: To evaluate the effectiveness of dronabinol (delta-9-THC) as supplementary therapy in a child with autistic disorder. Methods: A child who met the DSM-IV (Diagnostic and Statistical Manual of Mental…