Background:Â Dimethylheptyl-cannabidiol (DMH-CBD), a non-psychoactive, synthetic derivative of the phytocannabinoid cannabidiol (CBD), has been reported to be anti-inflammatory in RAW macrophages. Here, we evaluated the effects of DMH-CBD at the transcriptional…
Keyword: gene expression
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is the least understood genetically. Clinically, there are still limited therapeutic interventions…
Cannabinoid Receptor Type 2, but not Type 1, is Up-Regulated in Peripheral Blood Mononuclear Cells of Children Affected by Autistic Disorders
Autistic disorders (ADs) are heterogeneous neurodevelopmental disorders arised by the interaction of genes and environmental factors. Dysfunctions in social interaction and communication skills, repetitive and stereotypic verbal and non-verbal behaviours…
Role of CB2 receptors in social and aggressive behavior in male mice
Rationale Male CB1KO mice exhibit stronger aggressive responses than wild-type mice. Objective This study was designed to examine the role of cannabinoid CB2r in social and aggressive behavior. Methods The…