Keyword: glioblastoma multiforme


A Combined Preclinical Therapy of Cannabinoids and Temozolomide against Glioma

Abstract Glioblastoma multiforme (GBM) is highly resistant to current anticancer treatments, which makes it crucial to find new therapeutic strategies aimed at improving the poor prognosis of patients suffering from…

A pilot clinical study of D9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme

D9 -Tetrahydrocannabinol (THC) and other cannabinoids inhibit tumour growth and angiogenesis in animal models, so their potential application as antitumoral drugs has been suggested. However, the antitumoral effect of cannabinoids…

Cannabinoids selectively inhibit proliferation and induce death of cultured human glioblastoma multiforme cells

Normal tissue toxicity limits the efficacy of current treatment modalities for glioblastoma multiforme (GBM). We evaluated the influence of cannabinoids on cell proliferation, death, and morphology of human GBM cell…