Background: Some of cannabinoids, which are chemical compounds contained in marijuana, are immunosuppressive. One of the receptors, CB receptor 1 (CB1), is expressed predominantly by the cells in the central…
Keyword: JWH133
Chronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABAA receptors
BACKGROUND AND PURPOSE: The aim of this study was to explore the effects of CB2 receptor agonist and antagonist in the regulation of anxiety-like behaviours. EXPERIMENTAL APPROACHES: Effects of acute…
Role of CB2 receptors in social and aggressive behavior in male mice
Rationale Male CB1KO mice exhibit stronger aggressive responses than wild-type mice. Objective This study was designed to examine the role of cannabinoid CB2r in social and aggressive behavior. Methods The…