Inflammatory bowel disease (IBD) is an incurable disease which affects millions of people in industrialized countries. Anecdotal and scientific evidence suggests that Cannabis use may have a positive impact in…
Keyword: Macrophage/s
Effects of Cannabinoids on LPS-Stimulated Inflammatory Mediator Release From Macrophages: Involvement of Eicosanoids
D9 -Tetrahydrocannabinol (D9 -THC) is the major psychoactive component of marijuana and elicits pharmacological actions via cannabinoid receptors. Anandamide (AEA) and 2-arachidonoyl-glycerol (2-AG) are endogenous ligands for cannabinoid receptors, which…
Suppression of human macrophage interleukin-6 by a nonpsychoactive cannabinoid acid
Interleukin-6 (IL-6) is a multifunctional cytokine which contributes to inXammation and tissue injury in several diseases. Thus, inhibition of IL-6 production may be a useful strategy for treatment of patients…