Keyword: Marble burying test


Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice

Abstract Obsessive-compulsive disorder (OCD) is a common psychiatric disorder characterized by the occurrence of obsessions and compulsions. Glutamatergic abnormalities have been related to the pathophysiology of OCD. Cannabinoids inhibit glutamate…

Cannabidiol reverses the mCPP-induced increase in marble-burying behavior

Cannabidiol (CBD), one of the main components of Cannabis sp., presents clinical and preclinical anxiolytic properties. Recent results using the marble-burying test (MBT) suggest that CBD can also induce anticompulsive-like…