Please use this link to access this publication. Abstract The physiological and pathophysiological roles of the central nervous endogenous cannabinoid system are not completely understood, but still represent a challenge in basic…
Keyword: Nabilone
Comparison of analgesic effects and patient tolerability of nabilone and dihydrocodeine for chronic neuropathic pain: randomised, crossover, double blind study
Abstract Objective To compare the analgesic efficacy and side effects of the synthetic cannabinoid nabilone with those of the weak opioid dihydrocodeine for chronic neuropathic pain. Design Randomised, double blind, crossover trial…
Nabilone for the treatment of pain in fibromyalgia
Abstract A randomized, double-blind, placebo-controlled trial was conducted to determine the benefit of nabilone in pain management and quality of life improvement in 40 patients with fibromyalgia. After a baseline…
Use of cannabinoids for the treatment of patients with post-traumatic stress disorder
Abstract Objectives: Post-traumatic Stress Disorder (PTSD) is a diagnosis of extreme anxiety caused by a traumatic event. Less than 10% of individuals who have experienced severe trauma will develop this…
Use of a Synthetic Cannabinoid in a Correctional Population for Post-traumatic Stress Disorder Related Insomnia and Nightmares, Chronic Pain, Harm Reduction, and Other Indications
Abstract: Nabilone is a synthetic cannabinoid that has shown promise for the treatment of posttraumatic stress disorder (PTSD)Yrelated insomnia and nightmares as well as efficacy in the management of chronic…
The Use of a Synthetic Cannabinoid in the Management of Treatment-Resistant Nightmares in Posttraumatic Stress Disorder (PTSD)
This is the report of an open label clinical trial to evaluate the effects of nabilone, an endocannabinoid receptor agonist, on treatment-resistant nightmares in patients diagnosed with posttraumatic stress disorder…
Amyloid-beta inhibits E-S Potentiation through suppression of cannabinoid receptor 1 dependent synaptic disinhibition
Objective: The management of agitation in dementia is a growing problem and conventional modes of intervention have limited efficacy. Synthetic Cannabinoids have been studied in other conditions like pain and…
Cannabinoids and multiple sclerosis
There is a growing amount of evidence to suggest that cannabis and individual cannabinoids may be effective in suppressing certain symptoms of multiple sclerosis and spinal cord injury, including spasticity…
Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential
Bipolar affective disorder is often poorly controlled by prescribed drugs. Cannabis use is common in patients with this disorder and anecdotal reports suggest that some patients take it to alleviate…
Future of Cannabis and Cannabinoids in Therapeutics
This study reviews human clinical experience to date with several synthetic cannabinoids, including nabilone, levonantradol, ajulemic acid (CT3), dexanabinol (HU-211), HU-308, and SR141716 (Rimonabant®). Additionally, the concept of “clinical endogenous…