ABSTRACT Context: Chronic pain is highly prevalent in most of the industrialized nations around the world. Despite the documented adverse effects, opioids are widely used for pain management. Cannabinoids,…
Keyword: opioid/s
Medical Cannabis Use Is Associated With Decreased Opiate Medication Use in a Retrospective Cross-Sectional Survey of Patients With Chronic Pain
Abstract Opioids are commonly used to treat patients with chronic pain (CP), though there is little evidence that they are effective for long term CP treatment. Previous studies reported…
Medical Cannabis: Effects on Opioid and Benzodiazepine Requirements for Pain Control
The United States is currently undergoing a tragic opioid epidemic. We have a duty to try to curb this disaster. This study shows that by taking cannabis as an adjunct…
Cannabis as a substitute for prescription drugs – a cross-sectional study
Background: The use of medical cannabis is increasing, most commonly for pain, anxiety and depression. Emerging data suggest that use and abuse of prescription drugs may be decreasing in states…
Medical Cannabis Laws and Opioid Analgesic Overdose Mortality in the United States, 1999-2010
Opioid analgesic overdose mortality continues to rise in the United States, driven by increases in prescribing for chronic pain. Because chronic pain is a major indication for medical cannabis, laws that…
Prescribing cannabis for harm reduction
Abstract Neuropathic pain affects between 5% and 10% of the US population and can be refractory to treatment. Opioids may be recommended as a second-line pharmacotherapy but have risks including…
Synergistic affective analgesic interaction between delta-9-tetrahydrocannabinol and morphine
Evidence for an analgesic interaction between delta-9-tetrahydrocannabinol (Δ9 -THC) and morphine was sought using an experimental pain model applied to normal volunteers. The study incorporated a double blinded, four treatment,…