The recent legalization of cannabis for medical and recreational use in many states in the United States and internationally has resulted in a decrease in stigma and of perceived risk…
Keyword: sleep
Evaluation of the effects of CBD hemp extract on opioid use and quality of life indicators in chronic pain patients
ABSTRACT Context: Chronic pain is highly prevalent in most of the industrialized nations around the world. Despite the documented adverse effects, opioids are widely used for pain management. Cannabinoids,…
Medical cannabis for treatment-resistant combat PTSD
Abstract Targeting the endocannabinoid system may have a role in the treatment of post-traumatic stress disorder (PTSD). However, few studies have examined the effectiveness of cannabis on symptoms of PTSD,…
Medical cannabis and insomnia in older adults with chronic pain: a cross-sectional study
Having chronic pain can make it difficult to sleep through the night. And having a lack of sleep can compound the effects of any health issue, leading to a vicious…
A Longitudinal Study of Prenatal Marijuana Use Effects on Sleep and Arousal at Age 3 Years
Objective: To test the hypothesis that sleep disruptions would be evident in 3-year-old children with a history of prenatal marijuana exposure. Design: A prospective study using stratified random sampling beginning…
A Pilot Study into the Effects of the CB1 Cannabinoid Receptor Agonist WIN55,212-2 or the Antagonist/Inverse Agonist AM251 on Sleep in Rats
The plant cannabinoid Δ9-tetrahydrocannabinol and the endocannabinoid anandamide increase the amount of sleep via a CB1 receptor mediated mechanism. Here, we explored the use of a novel electroencephalogram (EEG) recording…
Around‐the‐Clock Oral THC Effects on Sleep in Male Chronic Daily Cannabis Smokers
Background and Objectives: D9‐tetrahydrocannabinol (THC) promotes sleep in animals; clinical use of THC is associated with somnolence. Human laboratory studies of oral THC have not shown consistent effects on sleep….
Potential Effects of Cannabidiol as a Wake-Promoting Agent
Over the last decades, the scientific interest in chemistry and pharmacology of cannabinoids has increased. Most attention has focused on Δ9 -tetrahydrocannabinol (Δ9 -THC) as it is the psychoactive constituent…
The effects of cannabinoid administration on sleep: a systematic review of human studies
This paper reviews the literature regarding the effects of cannabinoid administration on sleep in humans. A literature search using a set of cannabinoid and sleep-related terms was conducted across eight…