Keyword: ∆9-tetrahydrocannabinol (THC)


Use of cannabis for mental health in the Canadian territories: a cross-sectional study

Please use this link to access this publication. Abstract Background Population prevalence and patterns of cannabis use for mental health (CUMH) are underexplored. This is important to understand in the…

Cannabis and Public Health: A Study Assessing Regular Cannabis Users Through Health Indicators

Please use this link to access this publication. Abstract Background and Objective: An increasing number of countries are deciding to regulate the medicinal and/or recreational use of cannabis (Cannabis sativa L.). However,…

Acute Effects of Cannabis Inhalation on Arterial Stiffness, Vascular Endothelial Function, and Cardiac Function

Abstract Background The cardiovascular impact of cannabis use is incompletely understood. Although evidence links chronic use to an increased risk of disease and adverse cardiovascular events, few studies have investigated…

Serum Markers of Bone Turnover Following Controlled Administration of Two Medical Cannabis Products in Healthy Adults

Abstract Introduction: Cannabidiol (CBD) has been shown to maintain bone integrity in pre-clinical models, but little is known about the effects of delta-9-tetrahydrocannabinol (THC) on bone turnover. In this study we…

A semi-naturalistic open-label study examining the effect of prescribed medical cannabis use on simulated driving performance

Abstract Background: Despite increasing medical cannabis use, research has yet to establish whether and to what extent products containing delta-9-tetrahydrocannabinol (THC) impact driving performance among patients. Stable doses of prescribed…

Medical cannabis and its efficacy/effectiveness on the management of osteoarthritis pain and function

Please use this link to access this publication. Abstract Objective Despite pharmacological treatments for osteoarthritis (OA), more individuals are choosing medical cannabis for OA symptom management and for mitigating opioid…

The Effects of Stigma: Older Persons and Medicinal Cannabis

Abstract Cannabis has long been stigmatized as an illicit drug. Since legalization in Canada for both medical and recreational purposes, older adults’ cannabis consumption has increased more than any other…

Prenatal Cannabis Use and Maternal Pregnancy Outcomes

Abstract Importance: Many studies have evaluated whether in utero cannabis exposure is associated with fetal and neonatal outcomes, yet little is known about whether prenatal cannabis use is associated with maternal…

Bidirectional Effect of Long-Term Δ9-Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome

Abstract Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR) has a major impact on aging by regulating…

Cannabis and Cannabinoids in the Perioperative Period

Abstract Cannabis use is increasingly common, and with a growing number of jurisdictions implementing legalization frameworks, it is likely that providers will encounter more patients who use cannabis. Therefore, it…